Our world-class wound healing research laboratories based at Castle Hill Hospital include dedicated cell and tissue culture facilities (with bespoke live cell imaging capabilities), a well-equipped skin physiology testing suite, extensive histology, microbiology and imaging capabilities, complemented by state-of-the-art microbial metagenomics and transcriptomics technologies.
A major strength of the group is expertise across the full translational pipeline from molecular biology, human in vitro and ex vivo models, through to in vivo capabilities and first-in-man clinical studies.
The respiratory research centre houses state-of-the-art pre-clinical facilities for testing repurposed active pharmaceutical ingredients. This includes high throughput calcium signalling, ATP release assays, flow cytometry, western blotting, cell viability/proliferation assays, microscopy, qPCR and siRNA knockdowns.
We work closely with the Respiratory Clinical Trials Unit at Castle Hill Hospital, an internationally recognised centre of excellence in airway disease with Principal Investigators Professor Alyn Morice, Dr Simon Hart, and Dr Michael Crooks.