Research in the Centre for Atherothrombosis and Metabolic Disease (CAM) aims to increase our understanding of molecular and cellular mechanisms responsible for development of disease, and translate these findings into clinical benefits.

Our research includes programmes on chronic conditions such as cardiovascular disease, diabetes, chronic kidney disease, wound healing, infertility and airway inflammation. As these negatively impact quality of life and life expectancy, our goal is to develop new therapeutic approaches to manage these conditions.

Our research themes

Our innovative work tackles the following core themes – so we can ultimately improve the care for our patients and communities. Please explore each of these areas to discover details of the research taking place in our Centre.

Vascular biology and haemostasis

Our research is identifying new targets to develop innovative treatments to improve outcomes for patients with cardiovascular disease.

Wound healing

Management of wounds costs the NHS nearly £5 billion per year. We are developing innovative treatments for chronic wounds that will bring clinical and economic benefits.

Metabolism, reproduction and disease

We aim to discover how dynamic changes in metabolism in response to health, disease and lifestyle impact reproductive health and lead to the development of a range of non-communicable diseases.

Respiratory biology

Respiratory diseases are leading causes of death and disability in the world. Our aim is to understand the changes that occur in the airways in response to viruses, environmental stimuli and pharmaceuticals.

Skeletal muscle biology

Our research focuses on how nuclear hormone receptors could be targeted to enhance skeletal muscle fibre growth, maintenance and regeneration in metabolic and degenerative disorders associated with skeletal myopathies.