Innovation and translation

Below are a selection of examples of how our research is increasing the effectiveness of NHS services, provide value for money and benefit patients.

The Skin Research Centre covers the whole spectrum of skin research: from scientific discovery research, to applied research, clinical research and pilot production and manufacturing.

We are situated at Hull York Medical School, a partnership between the Universities of Hull and York, NHS Trusts and community healthcare providers.

As a result of this unique partnership, we have access to the expertise, facilities and research infrastructure and support that both universities and our NHS Trusts have to offer.

The Medical School’s partnership with regional NHS Trusts, GPs and community health organisations means that we have access to a wide clinical base within which to conduct skin research based on the needs of patients and for their direct benefit.

Skin microsampling technology

Developed by Professor Tarl Prow, the Director of the Skin Research Centre, microsampling technology offers a range of benefits that enhance patient experience and healthcare outcomes.

It is a minimally invasive procedure, causing less discomfort and pain compared to traditional biopsy methods. The technology is convenient and flexible, allowing skin biopsies to be performed either at home or in a clinic, which is particularly beneficial for patients with travel difficulties or those living in remote areas.

The procedure is quick, simple, and doesn't require any special preparation, reducing patient anxiety and stress.

Safety is also a key feature, as the device is designed to collect only a small skin tissue sample, thus minimizing the risk of infection or complications.

Furthermore, this technology is cost-effective, potentially reducing healthcare and research costs by enabling at-home collection and reducing the need for clinic visits.

The technology also facilitates personalised medicine by enabling easy and regular collection of skin tissue samples, which can be particularly beneficial in managing chronic skin conditions and advancing dermatological research.

ACORN (Acne Core Outcome Research Network)

Professor Alison Layton, Consultant Dermatologist and acne expert, is part of ACORN (Acne Core Outcome Research Network).

This network of international experts is working to improve outcomes for people with acne, through developing and delivering NIHR funded clinical trials and understanding the impact of microbiology and the microbiome in acne pathogenesis with the aim of developing novel therapeutics and reducing antimicrobial resistance.

Leishmaniasis

Professor Paul Kaye's main focus is on studying leishmaniasis, a neglected tropic disease that affects the immune system, with an estimated 700 000 to 1million new cases occur annually.

Professor Kaye is particularly interested in finding new ways to treat the disease by targeting the body's own defense mechanisms, as well as gaining a better understanding of how certain cells in the immune system work.

His ongoing work includes his internationally-recognised research the development and functions of macrophages and dendritic cells; investigating the factors that contribute to the disease's transmission to sand flies; understanding how leishmaniasis affects humans; and conducting clinical trials for a new vaccine.

Professor Kaye collaborates with partners in Brazil, India, Sri Lanka, and several countries in East Africa.