Study Title: Dafne Plus
A cluster randomised controlled trial of the DAFNEplus (Dose Adjustment for Normal Eating) intervention: A lifelong approach to promote effective self-management in adults with type 1 diabetes
Study Title: Hyper Aid
Hydrocortisone versus Prednisolone for Treatment of Adrenal Insufficiency Disease (HYPER-AID Study)
Study Title: Intralipid study
Effect of acute fluctuations of hyperlipidaemia on insulin resistance and cardiovascular risk in patients with type 2 diabetes
Study Title: HIPP
Osteoporotic hip fractures in older people: perspectives of service users and health care professionals on the impact of disease and post-fracture intervention
Study Title: PATRO
Post-Marketing Surveillance to monitor the long-term safety and efficacy of Omnitrope® in the treatment of adults
Study Title: SANTORINI
Treatment of High and Very high riSk dyslipidemic pAtients for the PreveNTion of CardiOvasculaR Events in Europe – a MultInatioNal ObservatIonal Study (SANTORINI)
Study Title: SELECT
Semaglutide effects on cardiovascular outcomes in people with overweight or obesity
Study Title: SOUL
Semaglutide cardiovascular outcomes trial in patients with type 2 diabetes (SOUL)
Study Title: SURE
A multi-centre, prospective, non-interventional study investigating the effectiveness of once-weekly subcutaneous semaglutide in a real world adult population with type 2 diabetes
Study title: SURPASS-CVOT
The Effect of Tirzepatide versus Dulaglutide on Major Adverse Cardiovascular Events in Patients with Type 2 Diabetes (SURPASS-CVOT)
Study title: TOPAZ
Treatment of osteogenesis imperfect with parathyroid hormone and Zoledronic acid
Study title: Vesalius
A Double-blind, Randomized, Placebo-controlled, Multicenter Study to Evaluate the Impact of Evolocumab on Major Cardiovascular Events in Patients at High Cardiovascular Risk Without Prior Myocardial Infarction or Stroke Short
Deshmukh H, Wilmot EG, Gregory R, Barnes D, Narendran P, Saunders S, Furlong N, Kamaruddin S, Banatwalla R, Herring R, Kilvert A, Patmore J, Walton C, Ryder REJ, Sathyapalan T. Effect of Flash Glucose Monitoring on Glycemic Control, Hypoglycemia, Diabetes-Related Distress, and Resource Utilization in the Association of British Clinical Diabetologists (ABCD) Nationwide Audit. Diabetes Care.2020;43(9):2153-2160.
Deshmukh H, Papageorgiou M, Aye M, England J, Abdalla M, Sathyapalan T. Hyperthyroidism and bone mineral density: Dissecting the causal association with Mendelian randomization analysis. Clin Endocrinol (Oxf).2020.
Deshmukh H, Aylward LL, Rose M, Fernandes A, Sedman P, Thatcher NJ, Atkin SL, Sathyapalan T. Association of endocrine active environmental compounds with body mass index and weight loss following bariatric surgery. Clin Endocrinol (Oxf).2020.
Moin ASM, Al-Qaissi A, Sathyapalan T, Atkin SL, Butler AE. Hypoglycemia in Type 2 Diabetes exacerbates Amyloid-related proteins associated with dementia. Diabetes Obes Metab.2020.
Moin ASM, Al-Qaissi A, Sathyapalan T, Atkin SL, Butler AE. Renin-Angiotensin System Overactivation in Type 2 Diabetes: A Risk for SARS-CoV-2 Infection? Diabetes Care.2020;43(10):e131-e133.
Mosenzon O, Blicher TM, Rosenlund S, Eriksson JW, Heller S, Hels OH, Pratley R, Sathyapalan T, Desouza C, Investigators P. Efficacy and safety of oral semaglutide in patients with type 2 diabetes and moderate renal impairment (PIONEER 5): a placebo-controlled, randomised, phase 3a trial. Lancet Diabetes Endocrinol.2019;7(7):515-527.
Deshmukh H, Papageorgiou M, Kilpatrick ES, Atkin SL, Sathyapalan T. Development of a novel risk prediction and risk stratification score for polycystic ovary syndrome. Clin Endocrinol (Oxf).2019;90(1):162-169.
Javed Z, Papageorgiou M, Deshmukh H, Rigby AS, Qamar U, Abbas J, Khan AY, Kilpatrick ES, Atkin SL, Sathyapalan T. Effects of empagliflozin on metabolic parameters in polycystic ovary syndrome: A randomized controlled study. Clin Endocrinol (Oxf).2019;90(6):805-813.
Javed Z, Papageorgiou M, Deshmukh H, Kilpatrick ES, Mann V, Corless L, Abouda G, Rigby AS, Atkin SL, Sathyapalan T. A Randomized, Controlled Trial of Vitamin D Supplementation on Cardiovascular Risk Factors, Hormones, and Liver Markers in Women with Polycystic Ovary Syndrome. Nutrients.2019;11(1).
Al-Qaissi A, Papageorgiou M, Javed Z, Heise T, Rigby AS, Garrett AT, Hepburn D, Kilpatrick ES, Atkin SL, Sathyapalan T. Environmental effects of ambient temperature and relative humidity on insulin pharmacodynamics in adults with type 1 diabetes mellitus. Diabetes Obes Metab.2019;21(3):569-574.
Al-Qaissi A, Papageorgiou M, Deshmukh H, Madden LA, Rigby A, Kilpatrick ES, Atkin SL, Sathyapalan T. Effects of acute insulin-induced hypoglycaemia on endothelial microparticles in adults with and without type 2 diabetes. Diabetes Obes Metab.2019;21(3):533-540.
Drage DS, Heffernan AL, Cunningham TK, Aylward LL, Mueller JF, Sathyapalan T, Atkin SL. Serum measures of hexabromocyclododecane (HBCDD) and polybrominated diphenyl ethers (PBDEs) in reproductive-aged women in the United Kingdom. Environ Res.2019;177:108631.
Butler AE, Hayat S, Dargham SR, Malek JA, Abdulla SA, Mohamoud YA, Suhre K, Sathyapalan T, Atkin SL. Alterations in long noncoding RNAs in women with and without polycystic ovarian syndrome. Clin Endocrinol (Oxf).2019;91(6):793-797.
Papageorgiou M, Sathyapalan T, Schutte R. Muscle mass measures and incident osteoporosis in a large cohort of postmenopausal women. J Cachexia Sarcopenia Muscle.2019;10(1):131-139.
Heffernan AL, Cunningham TK, Drage DS, Aylward LL, Thompson K, Vijayasarathy S, Mueller JF, Atkin SL, Sathyapalan T. Perfluorinated alkyl acids in the serum and follicular fluid of UK women with and without polycystic ovarian syndrome undergoing fertility treatment and associations with hormonal and metabolic parameters. Int J Hyg Environ Health.2018;221(7):1068-1075.
Chattopadhyay S, George A, John J, Sathyapalan T. Adjustment of the GRACE score by 2-hour post-load glucose improves prediction of long-term major adverse cardiac events in acute coronary syndrome in patients without known diabetes. Eur Heart J.2018;39(29):2740-2745.
Sathyapalan T, Al-Qaissi A, Kilpatrick ES, Dargham SR, Keevil B, Atkin SL. Salivary and serum androgens with anti-Mullerian hormone measurement for the diagnosis of polycystic ovary syndrome. Sci Rep.2018;8(1):3795
Sathyapalan T, Rigby AS, Bhasin S, Thatcher NJ, Kilpatrick ES, Atkin SL. Effect of Soy in Men With Type 2 Diabetes Mellitus and Subclinical Hypogonadism: A Randomized Controlled Study. J Clin Endocrinol Metab.2017;102(2):425-433.
Sathyapalan T, Aye M, Rigby AS, Fraser WD, Thatcher NJ, Kilpatrick ES, Atkin SL. Soy Reduces Bone Turnover Markers in Women During Early Menopause: A Randomized Controlled Trial. J Bone Miner Res.2017;32(1):157-164.
Current students
Najeeb Shah (MD) - Interventions on metabolic fluctuations on type 2 diabetes
Principal Supervisor: Professor Thozhukat Sathyapalan
Haidee Gonzalez (MD) - To evaluate the link between obesity, metabolic syndrome, hyperlipidaemia, NAFLD in inflammatory bowel disease
Principal Supervisor: Professor Thozhukat Sathyapalan
Mohammed Abdalla (PhD) - Pharmacotherapy of PCOS
Principal Supervisor: Professor Thozhukat Sathyapalan
Katie Bird (MD) - Evaluation of pharmacology prescribing assessment for undergraduate medical students
Principal Supervisor: Professor Thozhukat Sathyapalan
Alexandra Macnamara (MD) - Evaluation of pharmacology teaching for undergraudate medical students
Principal Supervisor: Professor Thozhukat Sathyapalan
Mo Aye (PhD) - Hull Hip fracture Intervention and Prevention Programme (HHIPP) (PhD 2019-2022) OSPREY (Osteoporosis research charity)
Principal Supervisor: Professor Thozhukat Sathyapalan
Youssra HZ Dakroury (MSc) - Vitamin D effects in Qatari population (MSc 2019-2020), Weill Cornell at Qatar
Principal Supervisor: Professor Thozhukat Sathyapalan
Saeed Alqarni (PhD) - Endoparticle profile in patients with type 2 diabetes
Co-supervisor: Professor Thozhukat Sathyapalan
Completed students
Alexandra Butler (PhD) - Life, Death and Regeneration for the Beta Cell (2020)
Principal Supervisor: Professor Thozhukat Sathyapalan
James England (MD) - Parameters for parathyroid surgery in hyperparathyroidism (2019)
Principal Supervisor: Professor Thozhukat Sathyapalan
Zeeshan Javed (PhD) - The effect of vitamin D in women with PCOS (2018)
Diabetes and Endocrinology research fund
Principal Supervisor: Professor Thozhukat Sathyapalan
Ahmed Al-Qaissi (MD) - The studies on the physiology of insulin action in patients with diabetes mellitus. (2018)
Principal Supervisor: Professor Thozhukat Sathyapalan
Alasdair O Doherty (PhD) - Effect of exercise of post-prandial hyperlipidaemia. (2016)
Co-supervisor: Professor Thozhukat Sathyapalan
Keith Cunningham (MD) -The impact of insulin resistance and polycystic ovary syndrome on IVF outcomes. (2016)
Principal Supervisor: Professor Thozhukat Sathyapalan
Ehtesham Ehtesham (PhD) - Effects of dietary polyphenols on vascular endothelium and cardiovascular health. (2016)
Principal Supervisor: Professor Thozhukat Sathyapalan
Constantine Simintiras (PhD) - The in vitro modelling of the oviduct: Investigating the role of maternal metabolic and endocrine parameters on early embryonic stem cell development (2014)
Co-supervisor: Professor Thozhukat Sathyapalan
Anish George (MD) - Effect of dysglycaemia on cardiovascular outcome following acute coronary syndrome. (2015)
Principal Supervisor: Professor Thozhukat Sathyapalan
Hassan Kahal (PhD) - The effect of liraglutide on platelet function and atherothormbotic risk in women with polycystic ovary syndrome (2015)
Principal Supervisor: Professor Thozhukat Sathyapalan
Judit Konya (MD) - Effect of polyphenols in cardiovascular risk factors. (2015)
Principal Supervisor: Professor Thozhukat Sathyapalan
Simon Adams (MD) - Identification of factors predictive of outcome following bariatric surgery (2013)
Principal Supervisor: Professor Thozhukat Sathyapalan
The use of digital technology in patients with type 1 diabetes attending transition clinic - Hull CCG, transformation funding - £20,000. 2018
Contigency funding for research nurse - Yorkshire and Humber CRN 2017-18 £15,307
Contingency funding from CRN Yorkshire and Humber (2016-17) - £30,894 (to HEY NHS Trust)
Measurement of stress hormones in hair - HEIF funding - (2016-17) £22,500
Hull Hip Fracture Intervention and Prevention Study (HHIPS). (2017-19) – Osteoporosis Research in East Yorkshire (OSPREY), UK. - Principal Investigator. £50,000
Service users’ perspectives in accessing type 2 services within Hull. (2016-17) Yorkshire and Humber Commissioning Support, UK – Principal Investigator. £22,864
Service users’ perspectives in accessing type 2 services within East Riding of Yorkshire. (2016-17) Yorkshire and Humber Commissioning Support, UK – Principal Investigator. £9,919.00