Mahe is a Clinical Trial Manager at Hull Health Trials Unit (HHTU). She is working on multiple clinical trials including international and national multicentre RCTs.
Mahe is a Clinical Trial Manager at HHTU (Hull Health Trial Unit) with a background in Nursing. She has extensive experience of working on international and national multicentre RCTs in different clinical areas such as respiratory, mental health & rare disease. Dedicated to delivering high-quality clinical trial research to utilize strong project management expertise to maximize recruitment and retention in clinical trials.
Matrix-Directed Therapy In Older Adolescents And Adults With Osteogenesis Imperfecta (MOI-A), UKRI & European commission (REMEDi4ALL), Phase II/pilot CTIMP, RCT.
Morphine and Breathlessness Study (MABEL) NIHR HTA Phase III CTIMP, RCT (National Study).Reviewing long term antidepressant use by careful monitoring in everyday practice (REDUCE) NIHR, Intervention study, RCT.
Evaluating the effectiveness and acceptability of free door to door transport to increase the uptake of breast screening appointments in Yorkshire: A cluster randomised GP pilot trial Picture (DOORSTEP).
REDUCE: REVIEWING LONG TERM ANTIDEPRESSANT USE BY CAREFUL MONITORING IN EVERYDAY PRACTICE.
Previous research:
MK-7264 (gefapixant): A 12 month study monitoring the effect of study drug MK-7264 over a 24 week main study period in adult participants with chronic cough (PN030).
GSK2798745: A placebo-controlled, double-blind (sponsor open), randomised, crossover study to assess the efficacy, safety, and tolerability of GSK2798745 in participants with chronic cough.
NOVELTY: D2287R00103 Observational study of obstructive lung diseaseVOLCANO-2: A DOUBLE-BLIND, RANDOMIZED, PLACEBO CONTROLLED STUDY IN CHRONIC COUGH
Synairgen: A study in COPD patientsTUF: The utility of FeNO in the differential diagnosis of chronic cough: The response to anti-inflammatory therapy with prednisolone and montelukast.
Full publications list:
http://orcid.org/0000-0002-0332-6933
Selected publications:
Sadeghi, M. H., et al. (2018). "Phenotyping patients with chronic cough: Evaluating the ability to predict the response to anti-inflammatory therapy." Ann Allergy Asthma Immunol 120(3): 285-291.
Sadeghi, M. H., Wright, C. E., Hart, S., Crooks, M. & Morice, A. H. (2017c) Does FeNO Predict Clinical Characteristics in Chronic Cough? Lung.
Sadeghi H, Morice A. The Emerging Role Of The Eosinophil And Its Measurement InChronic Cough. The Open Respiratory Medicine Journal 2017;11.
Sadeghi, M. H., Wright, C., Hart, S., Crooks, M. & Morice, A. (2017a) P105 Does feno predict clinical characteristics in chronic cough? Thorax, 72(Suppl 3), A140-A140.
Sadeghi, M. H., Wright, C., Hart, S., Crooks, M. & Morice, A. (2017b) S33 The utility of feno in the differential diagnosis of chronic cough: the response to anti-inflammatory therapy with prednisolone and montelukast. Thorax, 72(Suppl 3), A23-A24.