Main role is project managing a randomised controlled trial "REDUCE (Reviewing long term antidepressant use by careful monitoring in everyday practice)".
I am a health services researcher with a background in Nursing. I have previously worked on a number of studies within Respiratory Medicine, Clinical Trial Unit. I have conducted research on different grounds mainly on the diagnostic methods and treatments of chronic cough.
REDUCE: REVIEWING LONG TERM ANTIDEPRESSANT USE BY CAREFUL MONITORING IN EVERYDAY PRACTICE.
Previous research:
MK-7264 (gefapixant): A 12 month study monitoring the effect of study drug MK-7264 over a 24 week main study period in adult participants with chronic cough (PN030).
GSK2798745: A placebo-controlled, double-blind (sponsor open), randomised, crossover study to assess the efficacy, safety, and tolerability of GSK2798745 in participants with chronic cough.
NOVELTY: D2287R00103 Observational study of obstructive lung disease
VOLCANO-2: A DOUBLE-BLIND, RANDOMIZED, PLACEBO CONTROLLED STUDY IN CHRONIC COUGH
Synairgen: A study in COPD patients
TUF: The utility of FeNO in the differential diagnosis of chronic cough: The response to anti-inflammatory therapy with prednisolone and montelukast.
Full publications list:
http://orcid.org/0000-0002-0332-6933
Selected publications:
Sadeghi, M. H., et al. (2018). "Phenotyping patients with chronic cough: Evaluating the ability to predict the response to anti-inflammatory therapy." Ann Allergy Asthma Immunol 120(3): 285-291.
Sadeghi, M. H., Wright, C. E., Hart, S., Crooks, M. & Morice, A. H. (2017c) Does FeNO Predict Clinical Characteristics in Chronic Cough? Lung.
Sadeghi H, Morice A. The Emerging Role Of The Eosinophil And Its Measurement InChronic Cough. The Open Respiratory Medicine Journal 2017;11.
Sadeghi, M. H., Wright, C., Hart, S., Crooks, M. & Morice, A. (2017a) P105 Does feno predict clinical characteristics in chronic cough? Thorax, 72(Suppl 3), A140-A140.
Sadeghi, M. H., Wright, C., Hart, S., Crooks, M. & Morice, A. (2017b) S33 The utility of feno in the differential diagnosis of chronic cough: the response to anti-inflammatory therapy with prednisolone and montelukast. Thorax, 72(Suppl 3), A23-A24.