Dr Elmarie Myburgh

PhD

Lecturer in Immunology and Infection

Role at Hull York Medical School

I am a Lecturer in Immunology and Infection and my role includes teaching and research related to host-pathogen interactions, immunoregulation and drug discovery.

Biography

Elmarie Myburgh is a Lecturer (Assistant professor) in Immunology and Infection for Professor Kaye. She obtained a B.Sc (Biological Sciences) and an HonsB.Sc (Biochemistry) at the University of Stellenbosch, followed by a PhD in Infectious Immunology in Prof Frank Brombacher’s laboratory at the University of Cape Town, South Africa. She then relocated to the UK to do postdoctoral research in host-pathogen interactions and parasite biology in Jeremy Mottram's group at the Wellcome Trust Centre for Molecular Parasitology, University of Glasgow and later at the University of York.

Career

University of Stellenbosch

BSc in Biological Sciences

HonsB.Sc in Biochemistry

University of Cape Town, Institute of Infectious Disease and Molecular Medicine

PhD in Infectious Immunology

University of Glasgow, Wellcome Trust Centre for Molecular Parasitology

Postdoctoral Research Associate

Postdoctoral Research Fellow

University of York, York Biomedical Research Institute

Senior Postdoctoral Research Associate

Lecturer (Assistant professor) in Immunology and Infection

Research

My research focusses on the complex interplay between pathogens and their hosts, with a particular interest in the kinetoplastids Leishmania and African trypanosomes. I combine in vivo imaging approaches with genetic manipulation of host cells or pathogens to evaluate how pathogens establish infection to persist within the hostile host environment, but also how the mammalian host defends itself against acute and chronic infection. I apply these technologies for the identification of pathogen virulence factors, novel drug or immunotherapy targets and to support drug discovery programs.

Grants

Wellcome Trust Resource grant co-PI with J. Mottram (York), M. Barrett (University of Glasgow), S. Croft and J. Kelly (London School of Hygiene and Tropical Medicine). “In vivo screening resource to support drug development in parasitic disease” 2014-2017

SULSA Leaders Award (Scottish Universities Life Sciences Alliance) “Imaging host-parasite interaction to accelerate drug development” 2015 - 2016

Wellcome Trust/ ISSF Catalyst grant (University of Glasgow) co-PI with J. Rodgers and N. Dickens (University of Glasgow) “Comparative transcriptomic analysis of central nervous system and bloodstream-resident trypanosomes in murine model of human African trypanosomiasis” 2015 - 2017

Gates Grand Challenges Award co-PI with E. Devaney (Institute of Biodiversity Animal Health and Comparative Medicine, University of Glasgow “Illuminating the darkness: exploiting IVIS imaging technology” 2013 – 2015

Teaching

My teaching in the Hull York Medical School and Department of Biology is linked to my research interests in host-pathogen interactions, immunoregulation and drug discovery.

Lectures

  • Stage 2 Immunology and Infection
  • Stage 3 Mechanisms to Therapies

Tutorials

I provide small-group teaching to Hull York Medical School students in the Scholarship and Special Interest Programme(SSIP) and to Department of Biology students through tutorials

Hull York Medical School Year 1 SSIP on “Targeting host-pathogen interaction to treat disease”

Department of Biology Stage 2 tutorial on “Therapies against parasitic disease”

Projects

I supervise research projects for undergraduate Stage 3 and Stage 4 (integrated Masters), intercalating and postgraduate (masters and PhD) students. Topics are related to my research interests and include mainly lab-based projects.

Publications

Visit Dr Elmarie Myburgh's profile on the York Research Database to see a full list of publications, browse activities and projects, explore connections, collaborations, related work and more.