Professor David Allsup

BSc MB ChB PhD MRCP FRCPath FHEA

Professor of Haematology

Role at Hull York Medical School

David Allsup is a Professor of Haematology with an Honorary NHS appointment with Hull University Teaching Hospitals, based in the Queens Centre for Oncology and Haematology at Castle Hill Hospital.

His research interests include platelet disorders, the biology of chronic lymphocytic leukaemia, novel therapeutic approaches for haematological malignancies and supportive care for persons with blood cancers. I have led multiple translational and clinical research programmes which have resulted in high-impact journal outputs.

He is the local haemophilia director and has additional clinical interests in inherited and acquired platelet disorders. He is also the local lead for chronic lymphocytic leukaemia (CLL), in which he has a longstanding research interest.

Biography

Professor Allsup graduated from the University of Leicester with a degree in medicine in 1992 before undertaking general medical and haematological training in Sheffield and Liverpool. In 2000 he was appointed as a clinical lecturer in haematology during which time he investigated B-cell receptor signalling in chronic lymphocytic leukaemia.

He was appointed as a consultant haematologist in Hull University Teaching Hospitals NHS Trust in 2004 with specialist interests in chronic lymphocytic leukaemia and haemostasis. He continued with his research interests in chronic lymphocytic leukaemia and haemostasis and was appointed as Clinical Senior Lecturer in Haematology in the Hull York Medical School in 2018. In 2024 he was appointed as Professor of Haematology.

Research

Professor Allsup has multiple research interests related to the biology of chronic lymphocytic leukaemia, infection risk in persons with blood cancers and the supportive care of haematology patients. He jointly leads a NIHR funded clinical trial which investigates the optimal approach to the prevention of fungal infections in persons with leukaemia, the BioDrive trial. In addition, he collaborates with the centre for wound healing to investigate the fungal microbiome in blood cancer patients. He has a long-standing collaboration with Professor J Allan, University of Newcastle who investigates the genetic basis of chronic lymphocytic leukaemia. Locally he has supervised multiple PhD/MD/MSc projects related to CLL, infection risk in blood cancers and supportive care.

He is the local lead for platelet disorders and haemostasis and collaborates on multicentre studies investigated the cellular and genetic basis of inherited platelet disorders.

As well as an interest in fundamental biology, Professor Allsup also supports clinical research in Hull and has been local principle investigator on over forty phase II/III clinical trials, many of which have resulted in a change in clinical practice.

Teaching

David is enthusiastic about education and is actively involved in a variety of undergraduate teaching programmes.

He has contributed to:

  • Hull York Medical School phase I and II teaching programmes.
  • Hull York Medical School SSIP module.
  • Postgraduate medical teaching for core medical trainees and specialist trainees in haematology.
  • Development of e-learning materials for the administration of intrathecal chemotherapy and venous thromboembolism.
  • Supervision of postgraduate research degrees including MSc and PhD students.
  • Lectures on the MSc in Pharmacology and Drug Development Course.
  • Educational supervisor to haematology specialist trainees.
  • Supervisor for practitioners undertaking non-medical prescribing courses.
  • Examiner for MBBS programme.Internal and external examiner for postgraduate research degrees.
Publications

View David's publications on ORCID.

Collaborations

David is actively collaborating with the organisations listed below. He is always interested in any collaborative project that can advance patient care or the understanding of haematological diseases.

  • University of York Clinical Trials Unit, BioDrive Trial.
  • University of Newcastle, Professor J Allan. Constitutional genetics and chronic lymphocytic leukaemia.
  • Clinical trials unit, University of Leeds, member of the trial management group for the FLAIR and STATIC randomised clinical trials, chief investigator Dr T Munir.
Postgraduate research supervision

Professor Allsup is happy to offer research supervision to prospective PhD students with interests in chronic lymphocytic leukaemia, haematological cancers, platelet disorders and patient experience of care.

See PhD opportunities on FindAPhD.com

External roles

David is a member of the CLL clinical trials subgroup, the United Kingdom Haemophilia Centre Directors Organisation and the British Society of Haematology. He is also a Fellow of the Royal College of Pathologists.

He has also contributed to reviews and workshops for the National Institute of Clinical Excellence and the European Medicines Agency.

He has acted as a peer reviewer for mutliple funding agencies and journals.

He regularly contributes to patient engagement events run by national advocacy groups.