Dr Angela Hoye

MB ChB, PhD, FRCP

Consultant Cardiologist

Role at Hull York Medical School

In addition to contributing to the cardiology teaching of students in clinical training in Hull, I have two additional roles within HYMS. I am currently responsible for the Phase II SSC and SSIP parts of the curriculum and am a member of the Phase II curriculum committee. I am also one of the Senior Advisors based in Hull and offer pastoral support in a wide range of situations for a number of students.

Biography

Dr Angela Hoye MB ChB, PhD

Angela Hoye qualified in medicine at the University of Sheffield in 1993. She undertook Specialist Registrar training in Cardiology in East Yorkshire between 1998 and 2005, including a 2-year Interventional Cardiology Fellowship in Thoraxcentre, Rotterdam from 2002-2004. Her PhD was awarded in 2006 from the Erasmus University of Rotterdam following her work on the efficacy of drug-eluting stents for the treatment of complex coronary disease. She was appointed as an NHS Consultant in Hull in 2005 and moved to her current position as a Senior Lecturer in Cardiology in 2010.

 

Research

Dr Hoye`s research interests relate to percutaneous coronary intervention for patients with stable angina as well as acute coronary syndromes. Her research interests are focused in several key areas:

Chronic total occlusions:

Improved clinical assessment of patients with a chronic total coronary occlusion and also evaluation of the development and function of collaterals

Anti-platelet therapy:

In conjunction with Prof Naseem in Biomedical Sciences, she has also started work to evaluate anti-platelet therapy used in clinical practice. This work evaluates platelet function and anti-platelet efficacy in patients with coronary disease who are undergoing coronary stent implantation.

Coronary disease in Women:

Female patients with coronary artery disease tend to have poorer outcomes than their male counterparts, and are often under-represented in clinical trials. Dr Hoye is undertaking clinical research to try to understand some of the mechanisms to explain this apparent disparity.

Teaching

I deliver some of the Phase I cardiology lectures and in addition offer an SSC and SSIP in Interventional Cardiology.

Publications

 Dr Hoye has more than 70 publications in peer-reviewed journals. The following is a list of some of her publications obtained in the last 5 years.

  1. Collateral Donor Artery Physiology and the Influence of a Chronic Total Occlusion on Fractional Flow Reserve Ladwiniec A, Thackray ST, Alamgir F, Hoye A. Circulation and Cardiovascular Interventions 2015. 

  2. Long-term follow-up of elective chronic total coronary occlusion angioplasty: analysis from the U.K. Central Cardiac Audit Database.George S, Cockburn J, Clayton TC, Ludman P, Cotton J, Spratt J, Redwood S, de Belder M, de Belder A, Hill J, Hoye A, Palmer N, Rathore S, Gershlick A, Di Mario C, Hildick-Smith D; British Cardiovascular Intervention Society; National Institute for Cardiovascular Outcomes Research. J Am Coll Cardiol. 2014 Jul 22;64(3):235-43. 

  3. Noncardiac pathology exposed at coronary angiography for ST-segment elevation. Rossington JA, Balerdi M, Hoye AJ.JACC Cardiovasc Interv. 2014 May;7(5):e41-3. 

  4. Change in donor artery Fractional Flow Reserve After Recanalization of a Chronic Total Occlusion: Not as Impressive as Some Might Have Us Believe Ladwiniec A, Hoye A Catheterization and Cardiovascular Interventions 83:1190–1191 (2014)   

  5. Coronary Collaterals: A Little Give and Take, and a Few Unanswered Questions. Ladwiniec A, Hoye A. J Clin Exp Cardiolog 2013, 4:4  

  6. Examining access routes and bleeding risk in women undergoing percutaneous coronary intervention. Buchanan GL, Hoye A.Interventional Cardiology 08/2013; 5(4):419-425. 

  7. Intravenous versus intracoronary bolus of glycoprotein IIb/IIIa inhibitor administration during primary percutaneous coronary intervention on long-term left ventricular systolic and diastolic function. Pellicori P, Torromeo C, Barillà F, Mangieri E, Evangelista A, Truscelli G, Costanzo P, Hoye A, Wong K.Cardiol J. 2013;20(3):310-7.  

  8. Medical management of stable coronary atherosclerosis.Pellicori P, Costanzo P, Joseph AC, Hoye A, Atkin SL, Cleland JG.Curr Atheroscler Rep. 2013 Apr;15(4):313. 

  9. The occupational effects of interventional cardiology: results from the WIN for safety survey. Buchanan GL, Chieffo A, Mehilli J, Mikhail GW, Mauri F, Presbitero P, Grinfeld L, Petronio AS, Skelding KA, Hoye A, Mehran R, Morice MC. EuroIntervention. 2012 Oct 22;8(6):658-63.

  10.  Management of chronic total occlusions by percutaneous coronary intervention.  Hoye, A. Heart 2012;98:822-28 

  11. Focus on the research utility of intravascular ultrasound - comparison with other invasive modalities. Bourantas CV, Garg S, Naka KK, Thury A, Hoye A, Michalis LK.Cardiovasc Ultrasound. 2011 Jan 30;9(1):2. 

  12. Clinical indications for intravascular ultrasound imaging. Bourantas CV, Naka KK, Garg S, Thackray S, Papadopoulos D, Alamgir FM, Hoye A, Michalis LK.Echocardiography. 2010 Nov;27(10):1282-90.  

  13. Spontaneous coronary artery dissection: time for a concerted effort to better understand this rare condition.Hoye A.J Invasive Cardiol. 2010 May;22(5):229-30. 

  14. Gender disparity in patients undergoing percutaneous coronary intervention for acute coronary syndromes - does it still exist in contemporary practice? Jibran R, Khan JA, Hoye A.Ann Acad Med Singapore. 2010 Mar;39(3):173-8. 

  15. Gender-based issues in interventional cardiology: a consensus statement from the Women in Innovations (WIN) initiative.Chieffo A, Hoye A, Mauri F, Mikhail GW, Ammerer M, Grines C, Grinfeld L, Madan M, Presbitero P, Skelding KA, Weiner BH, Mehran R; WIN Group.EuroIntervention. 2010 Feb;5(7):773-9. Rev Esp Cardiol. 2010 Feb;63(2):200-8. Catheter Cardiovasc Interv. 2010 Feb 1;75(2):145-52. 

  16. Takotsubo cardiomyopathy: a review of the literature. Pernicova I, Garg S, Bourantas CV, Alamgir F, Hoye A. Angiology. 2010 Feb;61(2):166-73.

Collaborations

Currently collaborating with Prof K Naseem in Biomedical Sciences evaluating anti-platelet therapies.

also collaborating with Prof R Pudil (Charles University, University Hospital Hradec Kralove, Czech Republic) on a study to evaluate biomarkers of cereral ischaemia occurring during coronary angiography and angioplasty.

 

prof. Dr. Radek Pudil, Ph.D.

Charles University, Medical Faculty,

Department of Cardiology

University Hospital Hradec Kralove

Czech Republic