Professor Paul Kaye, Director of the HYMS Centre for Immunology and Infection, has been given a prestigious Wellcome Trust Senior Investigator Award, to continue his research on visceral leishmaniasis.
These awards are given by the Wellcome Trust to support exceptional, world-class researchers, who hold an established academic position.
Leishmaniasis is one of the major neglected diseases of poverty, affecting over one million people worldwide and the most severe form, visceral leishmaniasis or kala azar, is responsible for tens of thousands of deaths every year.
This parasitic disease is spread through the bite of a female sandfly, that itself has become infected by biting someone that is either sick from the disease or carrying the parasite without knowing it.
To develop tools that will help break the cycle of disease transmission, more needs to be known about how these parasites spread around the body, how they are acquired by sandflies and how variations in host immune response affects these processes.
Professor Kaye’s research addresses these questions using new models of leishmaniasis transmission, state of the art techniques in cellular immunology and molecular pathology, and computational modeling. The research will provide new knowledge directly applicable to the fight towards eliminating this devastating disease.
The preliminary research supporting this new program of work was conducted in bespoke facilities for sandfly research established at York using funds awarded through a Research Pump Priming Award from the Centre for Chronic Diseases and Disorders http://www.york.ac.uk/c2d2/
Prof Paul Kaye